FUSED PYRIDINE-DERIVATIVES FROM THE WITTIG REACTION OF SOME FLUORINATED AMIDES

被引：8

作者：

LATHAM, EJ ^{[1
]}

MURPHY, SM ^{[1
]}

STANFORTH, SP ^{[1
]}

机构：

[1] NORTHUMBRIA UNIV,DEPT CHEM & LIFE SCI,NEWCASTLE TYNE NE1 8ST,TYNE & WEAR,ENGLAND

来源：

TETRAHEDRON | 1995年 / 51卷 / 37期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1016/0040-4020(95)00605-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Compound 2 reacted with phosphorane 3 (R = Et) giving the quinoline derivative 5 whereas thiophenes 7 and 9 gave enamines 8 and 10 respectively with the appropriate phosphorane 3 (R = Me or Et). Pyridine derivative 11 yielded only ethyl 2-aminonicotinate with phosphorane 3 (R = Et). Compounds 8 and 10 gave the fused pyridine derivatives 14 and 15 respectively when treated with sodium hydride.

引用

页码：10385 / 10388

页数：4

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