LYMPHOMA DEVELOPING IN A PATIENT WITH RHEUMATOID-ARTHRITIS TAKING METHOTREXATE

被引：26

作者：

TAILLAN, B

GARNIER, G

CASTANET, J

FERRARI, E

PESCE, A

DUJARDIN, P

机构：

[1] Service de Médecine Interne, Hôpital de Cimiez, Nice Cedex 1, 06003

来源：

CLINICAL RHEUMATOLOGY | 1993年 / 12卷 / 01期

关键词：

LYMPHOMA; METHOTREXATE; RHEUMATOID ARTHRITIS;

D O I：

10.1007/BF02231567

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report one case of non-Hodgkin lymphoma in a patient, with a 30-year history of rheumatoid arthritis, taking low dose methotrexate weekly over a 10-month period. The mild immunosuppression that occurs with methotrexate therapy probably places patients with rheumatoid arthritis at added risk of developing lymphoproliferative diseases, but coincidence cannot be excluded.

引用

页码：93 / 94

页数：2

共 5 条

[1]

Weinblatt M.E., Coblyn J.S., Fox D.A., Et al., Efficacy of low dose methotrexate in rheumatoid arthritis, N Engl J Med, 312, pp. 818-822, (1985)

[2]

Kinlen L.J., Incidence of cancer in rheumatoid arthritis and other disorders after immunosuppressive treatment, Am J Med, 78, pp. 44-49, (1985)

[3]

Ellman M.H., Hurwitz H., Thomas C., Kozloff M., Lymphoma developing in a patient with rheumatoid arthritis taking low dose weekly methotrexate, J Rheumatol, 18, pp. 1741-1743, (1991)

[4]

Bailin P.L., Tindall J.P., Roenigh H.H., Et al., Is methotrexate therapy for psoriasis carcinogenic? A modified retrospective prospective analysis, JAMA, 232, pp. 359-362, (1975)

[5]

Shiroky J.B., Frost A., Skelton J.D., Et al., Complications of immunosuppression associated with weekly low dose methotrexate, J Rheumatol, 18, pp. 1172-1175, (1991)

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