BIOACTIVE COMPOUNDS FROM PSYCHOTRIA CAMPONUTANS

被引：59

作者：

SOLIS, PN

LANGAT, C

GUPTA, MP

KIRBY, GC

WARHURST, DC

PHILLIPSON, JD

机构：

[1] UNIV PANAMA,FAC FARM,CTR INVEST FARMACOGNOST,PANAMA CITY,PANAMA

[2] UNIV LONDON LONDON SCH HYG & TROP MED,DEPT MED PARASITOL,LONDON WC1E 7HT,ENGLAND

来源：

PLANTA MEDICA | 1995年 / 61卷 / 01期

基金：

英国惠康基金;

关键词：

PSYCHOTRIA CAMPONUTANS; CEPHAELIS CAMPONUTANS; RUBIACEAE; BIOACTIVE COMPOUNDS; 2-HYDROXYBENZOISOCHROMANQUINONE; BENZO[G]ISOQUINOLINE-5; 10-DIONE; BENZOQUINONE; BRINE SHRIMP; KB CELLS; PLASMODIUM FALCIPARUM;

D O I：

10.1055/s-2006-958001

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

A new benzoquinone (1-hydroxybenzoisochromanquinone) and benz[g]isoquinoline-5, 10-dione have been isolated from the woody parts of Psychotria camponutans, as a result of bioactivity-guided fractionation. The compounds were characterized by UV, IR, EI-mass,H-1-, and C-13-NMR, and HETCOR NMR spectroscopy. Both compounds, together with acetylbenzoisochromanquinone, showed in vitro strong activity against brine shrimp, KB cells, and chloroquine-resistant P. falciparum.

引用

页码：62 / 65

页数：4

共 14 条

[1]

INVITRO CYTOTOXICITY OF A SERIES OF QUASSINOIDS FROM BRUCEA-JAVA']JAVANICA FRUITS AGAINST KB CELLS [J].