EFFECTS OF AN INHIBITOR OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME-A REDUCTASE ON SERUM-LIPOPROTEINS AND UBIQUINONE-10 LEVELS IN PATIENTS WITH FAMILIAL HYPERCHOLESTEROLEMIA

被引：272

作者：

MABUCHI, H

HABA, T

TATAMI, R

MIYAMOTO, S

SAKAI, Y

WAKASUGI, T

WATANABE, A

KOIZUMI, J

TAKEDA, R

机构：

来源：

关键词：

D O I：

10.1056/NEJM198108273050902

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：478 / 482

页数：5

共 41 条

[1] ABE K, 1978, J NUTR SCI VITAMINOL, V24, P555, DOI 10.3177/jnsv.24.555
[2] MEVINOLIN - A HIGHLY POTENT COMPETITIVE INHIBITOR OF HYDROXYMETHYLGLUTARYL-COENZYME-A REDUCTASE AND A CHOLESTEROL-LOWERING AGENT
ALBERTS, AW
CHEN, J
KURON, G
HUNT, V
HUFF, J
HOFFMAN, C
ROTHROCK, J
LOPEZ, M
JOSHUA, H
HARRIS, E
PATCHETT, A
MONAGHAN, R
CURRIE, S
STAPLEY, E
ALBERSSCHONBERG, G
HENSENS, O
HIRSHFIELD, J
HOOGSTEEN, K
LIESCH, J
SPRINGER, J
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (07): : 3957 - 3961
[3] ALLAIN CC, 1974, CLIN CHEM, V20, P470
[4] [Anonymous], 1975, JAMA-J AM MED ASSOC, V231, P360
[5] BROWN MS, 1978, J BIOL CHEM, V253, P1121
[6] BROWN MS, 1980, J LIPID RES, V21, P505
[7] INHIBITION OF CELL-GROWTH BY OXYGENATED DERIVATIVES OF CHOLESTEROL
CHEN, HW
KANDUTSCH, AA
WAYMOUTH, C
[J]. NATURE, 1974, 251 (5474) : 419 - 421
[8] ENZYME TOPOLOGY OF INTRACELLULAR MEMBRANES
DEPIERRE, JW
ERNSTER, L
[J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1977, 46 : 201 - 262
[9] Eisenberg S, 1975, Adv Lipid Res, V13, P1
[10] ML-236A, ML-236B, AND ML-236C, NEW INHIBITORS OF CHOLESTEROGENESIS PRODUCED BY PENICILLIUM CITRINUM
ENDO, A
KURODA, M
TSUJITA, Y
[J]. JOURNAL OF ANTIBIOTICS, 1976, 29 (12) : 1346 - 1348