AABOMYCIN A, A NEW ANTIBIOTIC .I. PRODUCTION, ISOLATION AND PROPERTIES OF AABOMYCIN A

被引：10

作者：

AIZAWA, S

NAKAMURA, Y

SHIRATO, S

TAGUCHI, R

YAMAGUCHI, I

MISATO, T

机构：

[1] Kaken Chemical Co., Ltd., Tokyo

[2] Institute of Physical and Chemical Research, Saitama Prefecture, Yamato-machi

来源：

JOURNAL OF ANTIBIOTICS | 1969年 / 22卷 / 10期

关键词：

D O I：

10.7164/antibiotics.22.457

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Aabomycin A is a new antifungal antibiotic produced by a hitherto unidentified species of the genus Streptomyces. The active substance in fermented mash may be purified by solvent extraction followed by the chromatography on alumina column and then crystallization. Aabomycin A is easily soluble in many organic solvents, but is insoluble in water. It exhibits inhibitory activity against many fungi, especially against Piricularia oryzae, and has limited antiviral activity. The toxicity of aabomycin A for higher plants and animals is very low. Aabomycin A is similar in some properties to a few known antifungal antibiotics but differs from them in certain special characteristics. © 1969, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

引用

页码：457 / +

页数：1