RAPID, SENSITIVE METHOD FOR QUANTIFYING ENFLURANE IN WHOLE-BLOOD

被引：52

作者：

MILLER, MS ^{[1
]}

GANDOLFI, AJ ^{[1
]}

机构：

[1] UNIV ARIZONA,ARIZONA HLTH SCI CTR,DEPT ANESTHESIOL,PROGRAM TOXICOL,TUCSON,AZ 85724

来源：

ANESTHESIOLOGY | 1979年 / 51卷 / 06期

关键词：

D O I：

10.1097/00000542-197912000-00012

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Thermal conductivity detection (TCD) in conjunction with gas-liquid chromatography was employed for the analysis of enflurane in n-heptane extracts of whole blood. Enflurane was estimated to be 98 per cent extracted from whole blood by n-heptane. Analysis of enflurane standards ranging in concentration from 4.1 to 813 μM demonstrated linearity, with a correlation coefficient of 0.9999. As little as 8 μM enflurane may be detected in whole blood. TCD gas-liquid chromatography is a rapid and sensitive method for quantifying enflurane in whole blood.

引用

页码：542 / 544

页数：3