RELATIVE EFFICACY OF 2 ACELLULAR PERTUSSIS VACCINES DURING 3 YEARS OF PASSIVE SURVEILLANCE

被引：61

作者：

STORSAETER, J ^{[1
]}

OLIN, P ^{[1
]}

机构：

[1] NATL BACTERIOL LAB,S-10521 STOCKHOLM,SWEDEN

来源：

VACCINE | 1992年 / 10卷 / 03期

关键词：

PERTUSSIS; VACCINE EFFICACY; MONOCOMPONENT; 2-COMPONENT; RANDOMIZED TRIAL;

D O I：

10.1016/0264-410X(92)90002-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Prolonged unblinded passive surveillance of the trial cohort from the Swedish 1986-87 pertussis vaccine efficacy trial indicates that a two-component vaccine, containing pertussis toxoid and filamentous haemagglutinin, provided better long-term protection against pertussis than a monocomponent pertussis toxoid vaccine. The relative risk (RR) for culture-confirmed pertussis was 1.5 (95% confidence interval (CI) 1.0-2.4), and RR for pertussis according to parents' diagnoses was also 1.5 (95% CI 1.1-2.1), for the monocomponent vaccine compared with the two-component vaccine.

引用

页码：142 / 144

页数：3

共 17 条

[1]

[Anonymous], 1988, LANCET, Vi, P955

[2] PERTUSSIS PROPHYLAXIS WITH TWO DOSES OF ALUM-PRECIPITATED VACCINE [J].