SELECTIVE ALKYLATION - BIOMIMETIC REACTION OF ANTILEUKEMIC TRIPTOLIDES

被引：112

作者：

KUPCHAN, SM ^{[1
]}

SCHUBERT, RM ^{[1
]}

机构：

[1] UNIV VIRGINIA,DEPT CHEM,CHARLOTTESVILLE,VA 22901

来源：

SCIENCE | 1974年 / 185卷 / 4153期

关键词：

D O I：

10.1126/science.185.4153.791

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：791 / 793

页数：3

共 18 条

[1] NEIGHBORING HYDROXY-GROUP PARTICIPATION IN OPENING OF EPOXIDES BY NUCLEOPHILES
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[2] CONFORMATIONAL ANALYSIS OF CARBON-OXYGEN BOND OF ALCOHOLS USING JHCOH
BAULD, NL
RIM, YS
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[3] INHIBITION OF PHOSPHOFRUCTOKINASE BY QUINONE METHIDE AND ALPHA-METHYLENE LACTONE TUMOR INHIBITORS
HANSON, RL
LARDY, HA
KUPCHAN, SM
[J]. SCIENCE, 1970, 168 (3929) : 378 - &
[4] STEREOSPECIFIC HYDROXYL PROTON SPIN-SPIN COUPLING IN A PRIMARY ALCOHOL
KIEFER, EF
GERICKE, W
AMIMOTO, ST
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1968, 90 (22) : 6246 - &
[5] Kupchan S M, 1970, Trans N Y Acad Sci, V32, P85
[6] TUMOR INHIBITORS .69. STRUCTURE-CYTOTOXICITY RELATIONSHIPS AMONG SESQUITERPENE LACTONES
KUPCHAN, SM
EAKIN, MA
THOMAS, AM
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1971, 14 (12) : 1147 - &
[7] REACTIONS OF ALPHA METHYLENE LACTONE TUMOR INHIBITORS WITH MODEL BIOLOGICAL NUCLEOPHILES
KUPCHAN, SM
FESSLER, DC
EAKIN, MA
GIACOBBE, TJ
[J]. SCIENCE, 1970, 168 (3929) : 376 - &
[8] TUMOR INHIBITORS .74. TRIPTOLIDE AND TRIPDIOLIDE, NOVEL ANTILEUKEMIC DITERPENOID TRIEPOXIDES FROM TRIPTERYGIUM-WILFORDII
KUPCHAN, SM
BRYAN, RF
GILMORE, CJ
DAILEY, RG
COURT, WA
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1972, 94 (20) : 7194 - +
[9] KUPCHAN SM, IN PRESS
[10] REACTION OF BIOLOGICAL THIOLS WITH TUMOR INHIBITOR JATROPHONE - INHIBITION OF RNA-POLYMERASE
LILLEHAUG, JR
KLEPPE, K
SIGEL, CW
KUPCHAN, SM
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1973, 327 (01) : 92 - 100

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