EFFECT OF CHRONIC GM1 GANGLIOSIDE ADMINISTRATION ON PASSIVE-AVOIDANCE RETENTION IN MICE

被引：15

作者：

FAGIOLI, S

CASTELLANO, C

OLIVERIO, A

TOFFANO, G

机构：

[1] CNR,IST PSICOBIOL & PSICOFARMACOL,VIA RENO 1,I-00198 ROME,ITALY

[2] FIDIA RES LABS,ABANO TERME,ITALY

[3] UNIV ROME LA SAPIENZA,DIPARTIMENTO GENET & BIOL MOLEC,I-00185 ROME,ITALY

来源：

NEUROSCIENCE LETTERS | 1990年 / 109卷 / 1-2期

关键词：

Development; GM1; Memory; Mouse;

D O I：

10.1016/0304-3940(90)90565-Q

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Chronic administration of GM1 ganglioside to C57BL/6 mice during development improved passive avoidance retention. A significant weight increase was also evident in the treated animals in comparison with the control group. The results are discussed in terms of the possible effects exerted by GM1 upon the cholinergic mechanisms of this inbred strain. © 1990.

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页码：212 / 216

页数：5

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