IDENTIFICATION OF THE FACULTATIVE HETEROCHROMATIC X-CHROMOSOME IN FEMALES OF 25 RODENT SPECIES

被引:7
作者
KANDA, N
YOSIDA, TH
机构
[1] NATL INST GENET, DEPT CYTOGENET, YATA 1111, MISHIMA, SHIZUOKA 411, JAPAN
[2] TOKYO WOMENS MED COLL, DEPT ANAT, TOKYO 162, JAPAN
来源
CYTOGENETICS AND CELL GENETICS | 1979年 / 23卷 / 1-2期
关键词
D O I
10.1159/000131297
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Treatment of the chromosomes of 25 rodent species with a 50° C hypotonic solution and Giemsa staining permitted identification of the heterochromatic X chromosome in 24 species. With this technique, the facultative heterochromatic X chromosome or the facultative portion of large, composite-type X chromosomes is stained darker than the other chromosomes, allowing it to be distinguished from the homologous euchromatic X chromosome in female metaphase cells. Intense staining of the single X chromosome was not observed in male metaphase cells. It is suggested that this differential staining of one of the two X chromosomes might be due to qualitative differences in chromosomal proteins rather than to differences in the degree of chromosomal condensation or in DNA base sequence. © 1979 S. Karger AG, Basel.
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页码:12 / 22
页数:11
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