COGNITIVE BEHAVIORAL STRESS MANAGEMENT INTERVENTION BUFFERS DISTRESS RESPONSES AND IMMUNOLOGICAL CHANGES FOLLOWING NOTIFICATION OF HIV-1 SEROPOSITIVITY

被引:223
作者
ANTONI, MH
BAGGETT, L
IRONSON, G
LAPERRIERE, A
AUGUST, S
KLIMAS, N
SCHNEIDERMAN, N
FLETCHER, MA
机构
[1] UNIV MIAMI,CTR BIOPSYCHOSOCIAL STUDY AIDS,CORAL GABLES,FL 33124
[2] UNIV MIAMI,DEPT PSYCHIAT,CORAL GABLES,FL 33124
[3] UNIV MIAMI,DEPT MED,CORAL GABLES,FL 33124
关键词
D O I
10.1037/0022-006X.59.6.906
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
Forty-seven asymptomatic, healthy gay men were randomly assigned to a cognitive-behavioral stress management (CBSM) condition or an assessment-only control group 5 weeks before being notified of their HIV-1 antibody status. Seventy-two hours before and 1 week after serostatus notification, blood samples and psychometric data were collected. Control subjects showed significant increases in depression, but only slight decrements in mitogen responsivity and lymphocyte cell counts pre- to postnotification of seropositivity. Seropositive CBSM Ss did not show significant pre-post changes in depression, but did reveal significant increases in helper-inducer (CD4) and natural killer (CD56) cell counts as well as a slight increment in proliferative responses to phytohemagglutinin (PHA). Individual difference analyses suggest that the psychological buffering and immunomodulating effects of the CBSM manipulation may be attributable, in part, to relaxation skills learned and practiced or to a general willingness to comply with the intervention guidelines.
引用
收藏
页码:906 / 915
页数:10
相关论文
共 55 条
[1]  
American Psychiatric Association, 1980, DIAGN STAT MAN MENT, V3rd
[2]   PSYCHONEUROIMMUNOLOGY AND HIV-1 [J].
ANTONI, MH ;
SCHNEIDERMAN, N ;
FLETCHER, MA ;
GOLDSTEIN, DA ;
IRONSON, G ;
LAPERRIERE, A .
JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY, 1990, 58 (01) :38-49
[3]  
ANTONI MH, 1988, UNPUB COGNITIVE BEHA
[4]  
BARON GC, 1985, DIAGN CLIN IMMUNOL, V3, P197
[5]  
BECK AT, 1979, COGNITIVE THERAPY DE
[6]  
Bernstein D. A., 1973, PROGR RELAXATION TRA
[7]   A PSYCHOLOGICAL STUDY OF SURVIVORS AND NONSURVIVORS OF MYOCARDIAL INFARCTION [J].
BRUHN, JG ;
CHANDLER, B ;
WOLF, S .
PSYCHOSOMATIC MEDICINE, 1969, 31 (01) :8-&
[8]  
CALABRESE JR, 1987, AM J PSYCHIAT, V144, P1123
[9]   STRESS REDUCTION TRAINING CHANGED NUMBER OF SEXUAL PARTNERS BUT NOT IMMUNE FUNCTION IN MEN WITH HIV [J].
COATES, TJ ;
MCKUSICK, L ;
KUNO, R ;
STITES, DP .
AMERICAN JOURNAL OF PUBLIC HEALTH, 1989, 79 (07) :885-887
[10]  
CRARY B, 1983, J IMMUNOL, V130, P694