CORRELATION OF PHYSICOCHEMICAL PARAMETERS AND BIOLOGICAL-ACTIVITY IN STEROIDS - 9-ALPHA-SUBSTITUTED CORTISOL DERIVATIVES

被引：11

作者：

WOLFF, ME

HANSCH, C

机构：

[1] UNIV CALIF,SCH PHARM,DEPT PHARM CHEM,SAN FRANCISCO,CA 94122

[2] POMONA COLL,DEPT CHEM,CLAREMONT,CA 91713

来源：

EXPERIENTIA | 1973年 / 29卷 / 09期

关键词：

D O I：

10.1007/BF01946750

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：1111 / 1113

页数：3

共 19 条

[1]

BAUER N, 1960, PHYSICAL METHODS O 2, V1, pCH18

[2] A CORRELATION OF THYROXINE-LIKE ACTIVITY AND CHEMICAL STRUCTURE [J].

BRUICE, TC ;

KHARASCH, N ;

WINZLER, RJ .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1956, 62 (02) :305-317

[3]

BUSH IE, 1962, PHARMACOL REV, V14, P317

[4]

DRAPER N, 1966, APPLIED REGRESSION A

[5]

FREE SM, 1964, J MED CHEM, V7, P398

[6] BIOLOGICAL EFFECTS OF 9-ALPHA-FLUOROHYDROCORTISONE AND RELATED HALOGENATED STEROIDS IN ANIMALS [J].

FRIED, J .

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1955, 61 (02) :573-581

[7] SYNTHETIC DERIVATIVES OF CORTICAL HORMONES [J].

FRIED, J ;

BORMAN, A .

VITAMINS AND HORMONES, 1958, 16 :303-374

[8] LIPOPHILIC CHARACTER AND BIOLOGICAL-ACTIVITY OF DRUGS .2. PARABOLIC CASE [J].

HANSCH, C ;

CLAYTON, JM .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1973, 62 (01) :1-21

[9] EFFECT OF INTRAMOLECULAR HYDROPHOBIC BONDING ON PARTITION COEFFICIENTS [J].

HANSCH, C ;

ANDERSON, SM .

JOURNAL OF ORGANIC CHEMISTRY, 1967, 32 (08) :2583-&

[10]

HANSCH C, 1971, DRUG DESIGN

← 1 2 →