OVULATION-INDUCING ACTIVITY OF LULIBERIN (LHRH) COMPLEXED BY COPPER(II), NICKEL(II), AND ZINC(II) IONS

被引：16

作者：

KOZLOWSKI, H

MASIUKIEWICZ, E

POTARGOWICZ, E

RZESZOTARSKA, B

WALCZEWSKASUMOROK, A

机构：

[1] PEDAGOG UNIV OPOLE,INST CHEM,OPOLE,POLAND

[2] UNIV LODZ,INST PHYSIOL & BIOCHEM,LODZ,POLAND

来源：

JOURNAL OF INORGANIC BIOCHEMISTRY | 1990年 / 40卷 / 02期

关键词：

D O I：

10.1016/0162-0134(90)80045-Y

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have shown that the complexation of luteinizing hormone releasing hormone, luliberin (LHRH), a hypothalamic neurohormone, by Cu(II), Ni(II), and Zn(II) may affect its basic, ovulation-inducing potency in the dose responsive manner. Some explanation of the obtained results are offered here. © 1990.

引用

收藏

页码：121 / 125

页数：5

相关论文

共 31 条

[1] LHRH INTERACTION WITH ZN(II) IONS [J].

BAL, W ;

KOZLOWSKI, H ;

MASIUKIEWICZ, E ;

RZESZOTARSKA, B ;

SOVAGO, I .

JOURNAL OF INORGANIC BIOCHEMISTRY, 1989, 37 (02) :135-139

[2] EXTRACELLULAR CALCIUM IS REQUIRED FOR COPPER-AMPLIFIED PROSTAGLANDIN-E2 STIMULATION OF THE RELEASE OF GONADOTROPIN-RELEASING-HORMONE FROM MEDIAN-EMINENCE EXPLANTS [J].

BARNEA, A ;

CHO, G ;

COLOMBANIVIDAL, M .

ENDOCRINOLOGY, 1986, 119 (03) :1262-1267

[3] COPPER AMPLIFICATION OF PROSTAGLANDIN-E2 STIMULATION OF THE RELEASE OF LUTEINIZING-HORMONE-RELEASING HORMONE IS A POSTRECEPTOR EVENT [J].

BARNEA, A ;

CHO, G .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (02) :580-584

[4] AMPLIFICATION OF PROSTAGLANDIN-E2 STIMULATION OF LUTEINIZING-HORMONE-RELEASING HORMONE-RELEASE FROM MEDIAN-EMINENCE EXPLANTS - A METAL(II)-SPECIFIC EFFECT OF CHELATED COPPER [J].

BARNEA, A ;

CHO, G ;

COLOMBANIVIDAL, M .

BRAIN RESEARCH, 1986, 384 (01) :101-105

[5] EVIDENCE THAT A SHORT-LIVED EFFECT OF COPPER LEADS TO AMPLIFICATION OF PROSTAGLANDIN-E2 STIMULATION OF THE RELEASE OF GONADOTROPIN-RELEASING-HORMONE FROM MEDIAN-EMINENCE EXPLANTS [J].

BARNEA, A ;

CHO, G ;

COLOMBANIVIDAL, M .

ENDOCRINOLOGY, 1986, 119 (03) :1254-1261

[6] A LIGAND-SPECIFIC ACTION OF CHELATED COPPER ON HYPOTHALAMIC NEURONS - STIMULATION OF THE RELEASE OF LUTEINIZING-HORMONE-RELEASING HORMONE FROM MEDIAN-EMINENCE EXPLANTS [J].

BARNEA, A ;

COLOMBANIVIDAL, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (23) :7656-7660

[7] EVIDENCE THAT COPPER AMINO-ACID COMPLEXES ARE POTENT STIMULATORS OF THE RELEASE OF LUTEINIZING-HORMONE-RELEASING HORMONE FROM ISOLATED HYPOTHALAMIC GRANULES [J].

BARNEA, A ;

CHO, G .

ENDOCRINOLOGY, 1984, 115 (03) :936-943

[8] A ROLE FOR EXTRACELLULAR COPPER IN MODULATING PROSTAGLANDIN-E2 (PGE2) ACTION - FACILITATION OF PGE2 STIMULATION OF THE RELEASE OF GONADOTROPIN-RELEASING HORMONE (LHRH) FROM MEDIAN-EMINENCE EXPLANTS [J].

BARNEA, A ;

CHO, G ;

COLOMBANVIDAL, M .

ENDOCRINOLOGY, 1985, 117 (01) :415-417

[9] A CORRELATION BETWEEN THE LIGAND SPECIFICITY FOR COPPER-67 UPTAKE AND FOR COPPER-PROSTAGLANDIN-E2 STIMULATION OF THE RELEASE OF GONADOTROPIN-RELEASING HORMONE FROM MEDIAN-EMINENCE EXPLANTS [J].

BARNEA, A ;

CHO, G ;

HARTTER, DE .

ENDOCRINOLOGY, 1988, 122 (04) :1505-1510

[10]

BARNEA A, 1985, NEUROENDOCRINOLOGY, V41, P1499

← 1 2 3 4 →