TRANSCRIPTIONAL REGULATION OF MULTIGENE LOCI - MULTILEVEL CONTROL

被引：184

作者：

DILLON, N

GROSVELD, F

机构：

来源：

TRENDS IN GENETICS | 1993年 / 9卷 / 04期

关键词：

D O I：

10.1016/0168-9525(93)90208-Y

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Recent studies indicate that different levels of control operate within multigene loci. In addition to regulatory sequences immediately flanking the genes, there are also elements that act over long distances on more than one gene. Competition for these elements among genes can influence both the level and timing of gene expression during development.

引用

页码：134 / 137

页数：4

共 49 条

[1] EXPRESSION OF A BETA-GLOBIN GENE IS ENHANCED BY REMOTE SV40 DNA-SEQUENCES
BANERJI, J
RUSCONI, S
SCHAFFNER, W
[J]. CELL, 1981, 27 (02) : 299 - 308
[2] A SINGLE POINT MUTATION IS THE CAUSE OF THE GREEK FORM OF HEREDITARY PERSISTENCE OF FETAL HEMOGLOBIN
BERRY, M
GROSVELD, F
DILLON, N
[J]. NATURE, 1992, 358 (6386) : 499 - 502
[3] TISSUE SPECIFIC AND POSITION INDEPENDENT EXPRESSION OF THE COMPLETE GENE DOMAIN FOR CHICKEN LYSOZYME IN TRANSGENIC MICE
BONIFER, C
VIDAL, M
GROSVELD, F
SIPPEL, AE
[J]. EMBO JOURNAL, 1990, 9 (09) : 2843 - 2848
[4] DEVELOPMENTAL REGULATION OF BETA-GLOBIN GENE SWITCHING
CHOI, ORB
ENGEL, JD
[J]. CELL, 1988, 55 (01) : 17 - 26
[5] CHROMOSOMAL LOOP ANCHORAGE OF THE KAPPA IMMUNOGLOBULIN GENE OCCURS NEXT TO THE ENHANCER IN A REGION CONTAINING TOPOISOMERASE-II SITES
COCKERILL, PN
GARRARD, WT
[J]. CELL, 1986, 44 (02) : 273 - 282
[6] DEVILLIERS J, 1982, COLD SPRING HARB SYM, V47, P911
[7] HUMAN GAMMA-GLOBIN GENES SILENCED INDEPENDENTLY OF OTHER GENES IN THE BETA-GLOBIN LOCUS
DILLON, N
GROSVELD, F
[J]. NATURE, 1991, 350 (6315) : 252 - 254
[8] GAMMA-DELTA-BETA-THALASSEMIA DUE TO A DENOVO MUTATION DELETING THE 5' BETA-GLOBIN GENE ACTIVATION-REGION HYPERSENSITIVE SITES
DRISCOLL, MC
DOBKIN, CS
ALTER, BP
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (19) : 7470 - 7474
[9] MODULARITY IN PROMOTERS AND ENHANCERS
DYNAN, WS
[J]. CELL, 1989, 58 (01) : 1 - 4
[10] A DELETION OF THE HUMAN BETA-GLOBIN LOCUS ACTIVATION REGION CAUSES A MAJOR ALTERATION IN CHROMATIN STRUCTURE AND REPLICATION ACROSS THE ENTIRE BETA-GLOBIN LOCUS
FORRESTER, WC
EPNER, E
DRISCOLL, MC
ENVER, T
BRICE, M
PAPAYANNOPOULOU, T
GROUDINE, M
[J]. GENES & DEVELOPMENT, 1990, 4 (10) : 1637 - 1649

← 1 2 3 4 5 →