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ROLE OF TRANSFORMING GROWTH-FACTOR-BETA (TGF-BETA) IN SYSTEMIC AUTOIMMUNITY

被引：12
作者：
DELGIUDICE, G [1 ]
CROW, MK [1 ]
机构：
[1] NEW YORK HOSP CORNELL MED CTR,HOSP SPECIAL SURG,NEW YORK,NY 10021
来源：
LUPUS | 1993年 / 2卷 / 04期
关键词：
TGF-BETA; SLE; IMMUNOMODULATION; AUTOIMMUNITY; TISSUE REPAIR;
D O I：
10.1177/096120339300200402
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Transforming growth factor (TGF beta) is a multifunctional cytokine with proinflammatory as well as immunosuppressive activities. A regulatory role for TGF beta has been suggested in investigations of several experimental and spontaneous models of pathological autoreactivity. It is suggested that many of the functional effects of TGF beta parallel the major immune system abnormalities seen in SLE.
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页码：213 / 220
页数：8
相关论文
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