CLONING AND STRUCTURE OF CDNA-ENCODING ALPHA-LATROTOXIN FROM BLACK-WIDOW SPIDER VENOM

被引：102

作者：

KIYATKIN, NI

DULUBOVA, IE

CHEKHOVSKAYA, IA

GRISHIN, EV

机构：

[1] Shemyakin Institute of Bioorganic Chemistry, USSR Academy of Sciences, Moscow

来源：

FEBS LETTERS | 1990年 / 270卷 / 1-2期

关键词：

Amino acid sequence homology; cDNA nucleotide sequence; Deduced primary structure; α-Latrotoxin precursor;

D O I：

10.1016/0014-5793(90)81250-R

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

cDNA encoding the putative α-latrotoxin precursor was isolated from spider venom glands cDNA library and sequenced. The cDNA contained the 4203 base-pair open reading frame corresponding to the 156 855-Da protein composed of 1401 amino acids. Computer analysis of the deduced primary structure revealed the presence of various internal imperfect repeats mainly in its central and C-tenninal regions. © 1990.

引用

页码：127 / 131

页数：5

共 17 条

[1] MOLECULAR-CLONING, SEQUENCING, AND CHARACTERIZATION OF CDNA FOR SARCOTOXIN-IIA, AN INDUCIBLE ANTIBACTERIAL PROTEIN OF SARCOPHAGA-PEREGRINA (FLESH FLY) [J].