REGIO-SELECTIVE AND STEREOSELECTIVE SYNTHESIS OF 1,2-DISUBSTITUTED VINYLSILANES

被引：20

作者：

OBAYASHI, M ^{[1
]}

UTIMOTO, K ^{[1
]}

NOZAKI, H ^{[1
]}

机构：

[1] KYOTO UNIV,DEPT IND CHEM,KYOTO 606,JAPAN

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 1979年 / 177卷 / 01期

关键词：

D O I：

10.1016/S0022-328X(00)92339-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The alkylcopper reagents prepared from RMgBr and CuBr react with trimethylsilylacetylene to give regio- and stereo-selectivity 1-trimethylsilyl-1(Z)-alkenylcopper adducts. Hydrolysis affords 1-trimethylsilyl-1(E)-alkenes exclusively. Alkylation, acylation, halogenation, and stannylation proceed stereoselectively to afford synthetically useful intermediates. Homopropargylation of alkyl 1-trimethylsilyl-1(Z)-alkenylcuprates provided better yield than that of the original vinylcopper reagents. © 1979.

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页码：145 / 152

页数：8

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