ANTIBODY-AFFINITY AND PROTECTION IN VIRUS-INFECTIONS

被引：14

作者：

SALMI, AA

机构：

[1] University of Turku, Turku

来源：

CURRENT OPINION IN IMMUNOLOGY | 1991年 / 3卷 / 04期

关键词：

D O I：

10.1016/0952-7915(91)90011-O

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Affinity of viral antibodies matures slowly after primary virus infections. Recent investigations with human sera and mouse monoclonal antibodies have provided the first evidence for a role of antibody affinity in the pathogenesis of chronic virus infections. More detailed studies are necessary before the rules and exceptions of this phenomenon are revealed.

引用

页码：503 / 506

页数：4

共 26 条

[1] MUTATION DRIFT AND REPERTOIRE SHIFT IN THE MATURATION OF THE IMMUNE-RESPONSE [J].