ROLE OF SELENIUM AND OTHER TRACE-ELEMENTS IN THE GEOGRAPHY OF SCHIZOPHRENIA

被引:34
作者
BROWN, JS
机构
[1] Dept. of Psychiatry, Walter Reed Army Medical Center, Washington, DC
关键词
D O I
10.1093/schbul/20.2.387
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Medical geology is the application of trace element geography to epidemiology. This approach is used to compare the geographic distribution of selenium and other trace elements in soil and food with that of high schizophrenia rates in the United States and other countries. Since the comparison is most statistically significant for low selenium, the selenium theory of schizophrenia is evaluated by the principles of environmental epidemiology. Although this examination finds the theory deficient, research questions are generated to test the theory further and to investigate the causes of schizophrenia.
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页码:387 / 398
页数:12
相关论文
共 83 条
[1]  
Adriano D.C., 1986, TRACE ELEMENTS TERRE
[2]   SELENIUM CONCENTRATIONS IN BLOOD AND SERUM FROM PATIENTS WITH MENTAL DISEASES [J].
ALERTSEN, AR ;
AUKRUST, A ;
SKAUG, OE .
ACTA PSYCHIATRICA SCANDINAVICA, 1986, 74 (02) :217-219
[3]  
ALFTHAN G, 1989, SELENIUM BIOL MED, P210
[4]   SELENIUM MOLYBDENUM AND VANADIUM IN HUMAN BLOOD [J].
ALLAWAY, WH ;
KUBOTA, J ;
LOSEE, F ;
ROTH, M .
ARCHIVES OF ENVIRONMENTAL HEALTH, 1968, 16 (03) :342-&
[5]  
ANGINO EE, 1978, GEOCHEMISTRY ENV DIS, V3, P32
[6]  
[Anonymous], GEOCHEMISTRY ENV
[8]  
BOWIE SHU, 1985, ENV GEOCHEMISTRY HLT
[9]   HYDROPEROXY FATTY-ACID FORMATION IN SELENIUM DEFICIENT RAT PLATELETS - COUPLING OF GLUTATHIONE-PEROXIDASE TO THE LIPOXYGENASE PATHWAY [J].
BRYANT, RW ;
SIMON, TC ;
BAILEY, JM .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1983, 117 (01) :183-189
[10]  
Burton Robert, 1927, ANATOMY MELANCHOLY