THE ISOXAZOLINE ROUTE TO THE HYPOCHOLESTEROLEMIC AGENT COMPACTIN - USE OF THE ISOXAZOLINE AS A 1,3-DIENE EQUIVALENT

被引：52

作者：

KOZIKOWSKI, AP

LI, CS

机构：

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1987年 / 52卷 / 16期

关键词：

D O I：

10.1021/jo00392a009

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：3541 / 3552

页数：12

共 112 条

[1] DIHYDROMEVINOLIN, A POTENT HYPOCHOLESTEROLEMIC METABOLITE PRODUCED BY ASPERGILLUS-TERREUS [J].

ALBERSSCHONBERG, G ;

JOSHUA, H ;

LOPEZ, MB ;

HENSENS, OD ;

SPRINGER, JP ;

CHEN, J ;

OSTROVE, S ;

HOFFMAN, CH ;

ALBERTS, AW ;

PATCHETT, AA .

JOURNAL OF ANTIBIOTICS, 1981, 34 (05) :507-512

[2] MEVINOLIN - A HIGHLY POTENT COMPETITIVE INHIBITOR OF HYDROXYMETHYLGLUTARYL-COENZYME-A REDUCTASE AND A CHOLESTEROL-LOWERING AGENT [J].

ALBERTS, AW ;

CHEN, J ;

KURON, G ;

HUNT, V ;

HUFF, J ;

HOFFMAN, C ;

ROTHROCK, J ;

LOPEZ, M ;

JOSHUA, H ;

HARRIS, E ;

PATCHETT, A ;

MONAGHAN, R ;

CURRIE, S ;

STAPLEY, E ;

ALBERSSCHONBERG, G ;

HENSENS, O ;

HIRSHFIELD, J ;

HOOGSTEEN, K ;

LIESCH, J ;

SPRINGER, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (07) :3957-3961

[3] CONFORMATIONAL-ANALYSIS .130. MM2 - HYDROCARBON FORCE-FIELD UTILIZING V1 AND V2 TORSIONAL TERMS [J].

ALLINGER, NL .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1977, 99 (25) :8127-8134

[4] SILYL NITRONATES IN ORGANIC-SYNTHESIS - ROUTES TO HETEROCYCLES AND CYCLOPENTANOIDS - SYNTHESIS OF ALLETHROLONE AND CALYTHRONE - ACYLATION AND CYANOHYDROXYLATION OF DOUBLE-BONDS - AN EXPLORATORY-STUDY [J].

ANDERSEN, SH ;

DAS, NB ;

JORGENSEN, RD ;

KJELDSEN, G ;

KNUDSEN, JS ;

SHARMA, SC ;

TORSSELL, KBG .

ACTA CHEMICA SCANDINAVICA SERIES B-ORGANIC CHEMISTRY AND BIOCHEMISTRY, 1982, 36 (01) :1-14

[5] SYNTHETIC STUDIES RELATED TO COMPACTIN AND MEVINOLIN - A NEW SYNTHESIS OF THE HEXAHYDRONAPHTHALENE PORTION OF COMPACTIN [J].

ANDERSON, PC ;

CLIVE, DLJ ;

EVANS, CF .

TETRAHEDRON LETTERS, 1983, 24 (13) :1373-1376

[6] REACTIONS OF AN N-SULFONYLAMINE INNER SALT [J].

ATKINS, GM ;

BURGESS, EM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1968, 90 (17) :4744-&

[7]

BIBLE RH, 1961, J ORG CHEM, V26, P1336

[8] SESTERTERPENES .1. STEREOSPECIFIC CONSTRUCTION OF CEROPLASTOL AND OPHIOBOLIN RING-SYSTEMS VIA A COMMON BICYCLIC INTERMEDIATE [J].

BOECKMAN, RK ;

BERSHAS, JP ;

CLARDY, J ;

SOLHEIM, B .

JOURNAL OF ORGANIC CHEMISTRY, 1977, 42 (22) :3630-3633

[9] CRYSTAL AND MOLECULAR-STRUCTURE OF COMPACTIN, A NEW ANTIFUNGAL METABOLITE FROM PENICILLIUM-BREVICOMPACTUM [J].

BROWN, AG ;

SMALE, TC ;

KING, TJ ;

HASENKAMP, R ;

THOMPSON, RH .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1976, (11) :1165-1173

[10]

BROWN FK, 1985, THESIS U PITTSBURGH

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