CYTOSKELETAL PROTEINS OF THE CELL-SURFACE IN TETRAHYMENA .2. TURNOVER OF MAJOR PROTEINS

被引：21

作者：

VAUDAUX, PE ^{[1
]}

WILLIAMS, NE ^{[1
]}

机构：

[1] UNIV IOWA,DEPT ZOOL,IOWA CITY,IA 52242

来源：

EXPERIMENTAL CELL RESEARCH | 1979年 / 123卷 / 02期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/0014-4827(79)90474-9

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The turnover of surface membrane-associated cytoskeletal proteins has been studied in Tetrahymena. These proteins undergo rapid turnover and appear to be in equilibrium with precursor pools within the cytosol. Carefully controlled pulse-chase experiments, alone and in combination with cycloheximide, have shown that labeled proteins accumulated in the cytoskeleton after they were no longer being synthesized within the cell. The movement of subunits from the cytoskeleton to the cytosol was also demonstrated using tubulin isolated from these two compartments within the cell. © 1979.

引用

页码：321 / 331

页数：11

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