SMOKING HISTORY AND SURVIVAL AMONG LUNG-CANCER PATIENTS

被引:31
作者
GOODMAN, MT
KOLONEL, LN
WILKENS, LR
YOSHIZAWA, CN
LEMARCHAND, L
机构
关键词
CASE-CONTROL STUDY; LUNG CANCER; MORTALITY; SMOKING; SURVIVAL;
D O I
10.1007/BF00053167
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Two population-based case-control studies of lung cancer were conducted on the Island of Oahu, Hawaii, between 1979 and 1985. Interview information concerning smoking habits and other characteristics was obtained from a total of 463 men and 212 women with histologically confirmed lung cancer. Records from the Hawaii Tumor Registry were reviewed for information on the stage, histology, and follow-up status of these patients. Cigarette smoking was found to be positively related to the age-adjusted risk of death among women (relative risk (RR) = 1.6; 95 percent confidence interval (CI) = 1.0-2.4), but not among men (RR = 0.8; 95 percent CI = 0.5-1.2). Among women, the age-adjusted median survival time for never smokers was 33 months (n = 53) compared with a median survival of 18 months (n = 159) for smokers. Both past and current female smokers were at greater risk of death than never-smokers, and there was a significant trend in the risk of death by the number of cigarettes smoked per day (P = 0.04), and the age at which the subjects started smoking (P = 0.01). The effects of tumor stage and histology upon the association between tobacco smoking and survival were also explored.
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页码:155 / 163
页数:9
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