POSTINITIATION TRANSCRIPTIONAL CONTROL IN DROSOPHILA-MELANOGASTER

被引：174

作者：

ROUGVIE, AE ^{[1
]}

LIS, JT ^{[1
]}

机构：

[1] CORNELL UNIV,BIOCHEM MOLEC & CELL BIOL SECT,ITHACA,NY 14853

来源：

MOLECULAR AND CELLULAR BIOLOGY | 1990年 / 10卷 / 11期

关键词：

D O I：

10.1128/MCB.10.11.6041

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Drosophila hsp70 genes have an RNA polymerase II molecule paused at their 5' ends in uninduced cells. In this study we have shown that this pausing also occurs on other heat shock and constitutively expressed genes. We propose that a rate-limiting step in early elongation occurs in many Drosophila genes and may be a target for transcriptional regulation.

引用

页码：6041 / 6045

页数：5

共 32 条

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