A PILOT-STUDY ON THE EFFECT OF INTERFERON-ALPHA IN ATOPIC ECZEMA

被引：6

作者：

KROPP, JD

ALGERMISSEN, B

BUCK, S

CZARNETZKI, BM

机构：

来源：

HAUTARZT | 1994年 / 45卷 / 04期

关键词：

ATOPIC ECZEMA; IGE; INTERFERON-ALPHA; PRURITUS;

D O I：

10.1007/s001050050064

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

In this pilot study 12 patients with moderate to severe atopic eczema were treated with 2 million IU interferon alpha 2a (Roferon A) three times weekly for 8 weeks and followed up for a further 10 weeks: 2 patients showed clear and 9 a slight to moderate reduction of their skin lesions; 1 patient got worse. Pruritus did not decrease and even increased in a few patients, and IgE levels showed no change during and after treatment. All patients noted mild, transient, flu-like symptoms. The efficacy of interferon alpha in the present therapeutic design for the treatment of atopic eczema must thus be classified as only moderate.

引用

页码：225 / 227

页数：3

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