DIRECTED EXPRESSION OF NGF TO PANCREATIC BETA-CELLS IN TRANSGENIC MICE LEADS TO SELECTIVE HYPERINNERVATION OF THE ISLETS

被引：149

作者：

EDWARDS, RH

RUTTER, WJ

HANAHAN, D

机构：

[1] COLD SPRING HARBOR LAB,COLD SPRING HARBOR,NY 11724

[2] UNIV CALIF SAN FRANCISCO,DEPT BIOCHEM & BIOPHYS,SAN FRANCISCO,CA 94143

[3] UNIV CALIF SAN FRANCISCO,DEPT NEUROL,SAN FRANCISCO,CA 94143

来源：

CELL | 1989年 / 58卷 / 01期

关键词：

D O I：

10.1016/0092-8674(89)90412-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：161 / 170

页数：10

共 46 条

[1] NONTOLERANCE AND AUTOANTIBODIES TO A TRANSGENIC SELF ANTIGEN EXPRESSED IN PANCREATIC BETA-CELLS [J].

ADAMS, TE ;

ALPERT, S ;

HANAHAN, D .

NATURE, 1987, 325 (6101) :223-228

[2] HYBRID INSULIN GENES REVEAL A DEVELOPMENTAL LINEAGE FOR PANCREATIC ENDOCRINE-CELLS AND IMPLY A RELATIONSHIP WITH NEURONS [J].

ALPERT, S ;

HANAHAN, D ;

TEITELMAN, G .

CELL, 1988, 53 (02) :295-308

[3] ANALYSIS OF EFFECTS OF ANTISERUM TO NERVE GROWTH FACTOR IN ADULT MICE [J].

ANGELETTI, PU ;

LEVIMONT.R ;

CARAMIA, F .

BRAIN RESEARCH, 1971, 27 (02) :343-+

[4]

[Anonymous], 1986, MANIPULATING MOUSE E

[5] CELLULAR-LOCALIZATION OF NERVE GROWTH-FACTOR SYNTHESIS BY INSITU HYBRIDIZATION [J].

BANDTLOW, CE ;

HEUMANN, R ;

SCHWAB, ME ;

THOENEN, H .

EMBO JOURNAL, 1987, 6 (04) :891-899

[6] ACETYLCHOLINESTERASE NEURONS IN DOPAMINE-CONTAINING REGIONS OF BRAIN [J].

BUTCHER, LL ;

TALBOT, K ;

BILEZIKJIAN, L .

JOURNAL OF NEURAL TRANSMISSION, 1975, 37 (02) :127-153

[7] DEVELOPMENT OF SYMPATHETIC NEURONS IN COMPARTMENTALIZED CULTURES .2. LOCAL-CONTROL OF NEURITE SURVIVAL BY NERVE GROWTH-FACTOR [J].

CAMPENOT, RB .

DEVELOPMENTAL BIOLOGY, 1982, 93 (01) :13-21

[8] DEVELOPMENT OF SYMPATHETIC NEURONS IN COMPARTMENTALIZED CULTURES .1. LOCAL-CONTROL OF NEURITE GROWTH BY NERVE GROWTH-FACTOR [J].

CAMPENOT, RB .

DEVELOPMENTAL BIOLOGY, 1982, 93 (01) :1-12

[9] ROLE OF NERVE GROWTH-FACTOR IN DEVELOPMENT OF RAT SYMPATHETIC NEURONS INVITRO .1. SURVIVAL, GROWTH, AND DIFFERENTIATION OF CATECHOLAMINE PRODUCTION [J].

CHUN, LLY ;

PATTERSON, PH .

JOURNAL OF CELL BIOLOGY, 1977, 75 (03) :694-704

[10] DIFFERENT FACTORS FROM THE CENTRAL-NERVOUS-SYSTEM AND PERIPHERY REGULATE THE SURVIVAL OF SENSORY NEURONS [J].

DAVIES, AM ;

THOENEN, H ;

BARDE, YA .

NATURE, 1986, 319 (6053) :497-499

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