IMPROVED COUPLING OF PROTECTED PEPTIDES ON THE KAISER OXIME RESIN USING BOP ACTIVATION

被引：12

作者：

JARRETT, JT ^{[1
]}

LANSBURY, PT ^{[1
]}

机构：

[1] MIT,DEPT CHEM,CAMBRIDGE,MA 02139

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 32期

关键词：

D O I：

10.1016/S0040-4039(00)97676-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Protected peptides and amino acids can be coupled to resin-bound amine in high yield with low levels of racemization using BOP activation. The synthesis of the 16 amino acid protected peptide VI derived from the ice nucleation protein is described and experimental procedures for these couplings are provided. © 1990.

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页码：4561 / 4564

页数：4

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