SCP APPLICATION OR B15 STIMULATION ACTIVATES CAPK IN THE ARC MUSCLE OF APLYSIA

被引：14

作者：

HOOPER, SL

PROBST, WC

CROPPER, EC

KUPFERMANN, I

WEISS, KR

机构：

[1] CUNY MT SINAI SCH MED,DEPT PHYSIOL & BIOPHYS,NEW YORK,NY 10022

[2] COLUMBIA UNIV,P&S,CTR NEUROBIOL & BEHAV,NEW YORK,NY 10032

[3] NEW YORK STATE PSYCHIAT INST & HOSP,NEW YORK,NY 10032

来源：

BRAIN RESEARCH | 1994年 / 657卷 / 1-2期

关键词：

NEUROMODULATION; PEPTIDE; 2ND MESSENGER; INVERTEBRATE; CAMP; FEEDING; BUCCAL; CAMP-DEPENDENT PROTEIN KINASE; COTRANSMITTER;

D O I：

10.1016/0006-8993(94)90988-1

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Application of small cardioactive peptide (SCP) or stimulation of motorneuron B15 increases the level of activated cAMP-dependent protein kinase (cAPK) in the ARC muscle. SCP application also appears to induce a translocation of cAPK between different subcellular compartments of the ARC muscle and this translocation is also induced by cAMP addition to muscle homogenates. These results suggest that the actions of SCP in the Aplysia ARC neuromuscular system are mediated via the cAPK signal transduction pathway.

引用

页码：337 / 341

页数：5

共 21 条

[1] CARR DW, 1993, J BIOL CHEM, V268, P20729
[2] CROPPER E C, 1991, Society for Neuroscience Abstracts, V17, P1305
[3] DIFFERENTIAL FIRING PATTERNS OF THE PEPTIDE-CONTAINING CHOLINERGIC MOTOR NEURONS B15 AND B16 DURING FEEDING-BEHAVIOR IN APLYSIA
CROPPER, EC
KUPFERMANN, I
WEISS, KR
[J]. BRAIN RESEARCH, 1990, 522 (01) : 176 - 179
[4] MULTIPLE NEUROPEPTIDES IN CHOLINERGIC MOTOR NEURONS OF APLYSIA - EVIDENCE FOR MODULATION INTRINSIC TO THE MOTOR CIRCUIT
CROPPER, EC
LLOYD, PE
REED, W
TENENBAUM, R
KUPFERMANN, I
WEISS, KR
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (10) : 3486 - 3490
[5] RELEASE OF PEPTIDE COTRANSMITTERS FROM A CHOLINERGIC MOTOR NEURON UNDER PHYSIOLOGICAL CONDITIONS
CROPPER, EC
PRICE, D
TENENBAUM, R
KUPFERMANN, I
WEISS, KR
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (03) : 933 - 937
[6] HIRSCH AH, 1992, J BIOL CHEM, V267, P2131
[7] HOOPER SL, 1992, SOC NEUR ABSTR, V18, P1105
[8] FEEDING BEHAVIOR IN APLYSIA - SIMPLE SYSTEM FOR STUDY OF MOTIVATION
KUPFERMANN, I
[J]. BEHAVIORAL BIOLOGY, 1974, 10 (01): : 1 - 26
[9] KURASAWA A, 1979, MOL PHARMACOL, V15, P115
[10] LAKS MS, 1981, J BIOL CHEM, V256, P8775

← 1 2 3 →