ALPHA-L-FUCOSYLTRANSFERASES IN HUMAN SUBMAXILLARY GLAND AND SOMACH TISSUES ASSOCIATED WITH H LEA AND LEB BLOOD-GROUP CHARACTERS AND ABH SECRETOR STATUS

Schemes for the biosynthetic steps in the formation of the blood group active glycoproteins in secretions postulate that α-L-fucosyltransferases specified by the H and Le genes control the addition of L-fucose to different acceptor sites in a precursor substance to give H, Lea and Leb serologically active structures. 1,2. The presence of 2-, 3- and 4-α-L-fucosyl-transferases in submaxillary glands and stomach mucosal linings from persons who are secretors of ABH, and of 3- and 4-α-L-fucosyltransferases in tissues from non-secretor persons, is described in this paper. © 1969.