A GENERAL-ROUTE TO CARBA-PEPTIDE BOND REPLACEMENTS - UNEQUIVOCAL SYNTHESIS OF BOC-L-PHE-PSI(CH2-CH2)-L-ALA-OH AND BOC-L-PHE-PSI(CH2-CH2)-D-ALA-OH

被引：32

作者：

RODRIGUEZ, M ^{[1
]}

AUMELAS, A ^{[1
]}

MARTINEZ, J ^{[1
]}

机构：

[1] CNRS,CTR PHARMACOL ENDOCRINOL,INSERM,RUE CARDONILLE,F-34094 MONTPELLIER 05,FRANCE

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 36期

关键词：

D O I：

10.1016/S0040-4039(00)97829-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An unambiguous synthesis of Boc-L-Phe-Ψ(CH2-CH2)-L-Ala-OH and Boc-L-PheΨ(CH2-CH2)-D-Ala-OH from Boc-L-phenylalanine, through lactame intermediates (3R,6R)-3-methyl 6-benzyl-piperidin-2-one and (3S,6R)-3-methyl 6-benzyl-piperidin-2-one, is described. © 1990.

引用

页码：5153 / 5156

页数：4

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