EFFECT OF SERUM-LIPID CONCENTRATIONS ON RESTENOSIS AFTER SUCCESSFUL DE-NOVO PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY IN PATIENTS WITH TOTAL CHOLESTEROL 160 TO 240 MG/DL AND TRIGLYCERIDES LESS-THAN-350 MG/DL

The present study is the first to demonstrate a possible role of triglycerides and HDL cholesterol in the multifactorial process of restenosis using validated computerized quantitative angiographic analysis in a group of patients with normal or only mildly elevated total and LDL cholesterol. The results of this study require validation by a prospective study in unselected consecutive patients undergoing PTCA. If these results are confirmed, a prospective randomized trial would then be appropriate to test strategies to lower the total/HDL cholesterol ratio, possibly using combination therapy targeting triglycerides and HDL cholesterol as well as LDL cholesterol. © 1995 Excerpta Medica, Inc. All rights reserved under the United States, International, and Pan-American Copyright Conventions.