EFFECT OF BOVINE PANCREATIC POLYPEPTIDE ON BASAL PANCREATIC AND BILIARY OUTPUTS IN MAN

被引：83

作者：

GREENBERG, GR ^{[1
]}

MCCLOY, RF ^{[1
]}

CHADWICK, VS ^{[1
]}

ADRIAN, TE ^{[1
]}

BARON, JH ^{[1
]}

BLOOM, SR ^{[1
]}

机构：

[1] ROYAL POSTGRAD MED SCH,DEPT MED,DU CANE RD,LONDON W12 0HS,ENGLAND

来源：

DIGESTIVE DISEASES AND SCIENCES | 1979年 / 24卷 / 01期

关键词：

D O I：

10.1007/BF01297231

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Basal pancreatic and biliary outputs were examined in seven healthy volunteers during intravenous infusion of bovine pancreatic polypeptide (BPP) at a mean dose of 320 pmoll kg/hr. BPP significantly (P<0.02) inhibited outputs of trypsin and bilirubin, without affecting bicarbonate. These studies suggest the possibility that pancreatic polypeptide may have a role in the regulation of biliary and pancreatic enzyme secretion in man. © 1979 Digestive Disease Systems, Inc.

引用

页码：11 / 14

页数：4

共 17 条

[1] ADRIAN TE, 1976, GUT, V17, P393
[2] ADRIAN TE, 1977, LANCET, V1, P161
[3] DISTRIBUTION AND RELEASE OF HUMAN PANCREATIC POLYPEPTIDE
ADRIAN, TE
BLOOM, SR
BRYANT, MG
POLAK, JM
HEITZ, P
BARNES, AJ
[J]. GUT, 1976, 17 (12) : 940 - 944
[4] CHANCE RE, 1975, PROG ENDOCRINOL SOC, V163
[5] Floyd J C Jr, 1976, Trans Assoc Am Physicians, V89, P146
[6] GREENBERG GR, 1977, GUT, V18, pA978
[7] GREENBERG GR, ACTA HEPATO GASTROEN
[8] COMPARISON OF BOOTS AND GIH SECRETIN AS STIMULI OF PANCREATIC-SECRETION IN HUMAN SUBJECTS WITH OR WITHOUT CHRONIC PANCREATITIS
GUTIERREZ, LV
BARON, JH
[J]. GUT, 1972, 13 (09) : 721 - +
[9] PLASMA SECRETIN AND PANCREATIC BICARBONATE RESPONSE TO EXOGENOUS SECRETIN IN MAN
HACKI, WH
BLOOM, SR
MITZNEGG, P
DOMSCHKE, W
DOMSCHKE, S
BELOHLAVEK, D
DEMLING, L
WUNSCH, E
[J]. GUT, 1977, 18 (03) : 191 - 195
[10] HALLGREN R, 1977, SCAND J GASTROENTERO, V12, P923

← 1 2 →