INDUCTION OF CYANIDE-RESISTANT RESPIRATION BY SULFUR-COMPOUNDS IN HANSENULA-ANOMALA

被引：15

作者：

MINAGAWA, N

SAKAJO, S

YOSHIMOTO, A

机构：

[1] Department of Biochemistry, Niigata College of Pharmacy, Niigata, 950-21

来源：

AGRICULTURAL AND BIOLOGICAL CHEMISTRY | 1991年 / 55卷 / 06期

关键词：

D O I：

10.1080/00021369.1991.10870803

中图分类号：

S3 [农学（农艺学）];

学科分类号：

0901 ;

摘要：

Cyanide-resistant respiration was induced in Hansenula anomala in the presence of various sulfur compounds, having no inhibitory effect on the normal cytochrome pathway. This induction was observed in the presence of glucose. The mitochondrial 36 kDa protein responsible for cyanide-resistant respiration was also detected in the cells where cyanide-resistant respiration was induced by oxidized glutathione, indicating that there might be a common mechanism to initiate the biosynthesis of the protein. All the inducing conditions are deduced to increase the generation of superoxide anion, and some radical scavengers inhibited the induction, suggesting the possible involvement of certain active oxygen species in the initial induction process.

引用

页码：1573 / 1578

页数：6

共 26 条

[1] URIC-ACID PROVIDES AN ANTIOXIDANT DEFENSE IN HUMANS AGAINST OXIDANT-CAUSED AND RADICAL-CAUSED AGING AND CANCER - A HYPOTHESIS [J].