PHENYLETHYLAMINERGIC MECHANISMS IN ATTENTION-DEFICIT DISORDER

被引:52
作者
BAKER, GB [1 ]
BORNSTEIN, RA [1 ]
ROUGET, AC [1 ]
ASHTON, SE [1 ]
VANMUYDEN, JC [1 ]
COUTTS, RT [1 ]
机构
[1] OHIO STATE UNIV,DEPT PSYCHIAT,COLUMBUS,OH 43210
基金
美国国家卫生研究院;
关键词
D O I
10.1016/0006-3223(91)90207-3
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Urinary excretion (24-hr) of beta-phenylethylamine (PEA), phenylacetic acid (PAA), phenylalanine (Phe), and p-tyrosine (Tyr), and plasma levels of PAA, Phe, and Tyr were examined in 18 normal children and 26 children diagnosed as having attention-deficit hyperactivity disorder (ADHD). The results indicated that urinary excretion (expressed per g of creatinine) of free and total PEA was significantly lower in the ADHD patients, and plasma levels of Phe and Tyr were also decreased in the ADHD subjects compared with the normal controls.
引用
收藏
页码:15 / 22
页数:8
相关论文
共 46 条