ANTICANCER AGENT CHLOROQUINOXALINE SULFONAMIDE

The crystal structure of the antitumor agent 4-amino-N-(5-chloro-2-quinoxalinyl)benzenesulfonamide, C14H11ClN4O2S, has been determined by X-ray diffraction methods. The geometry around the S atom is distorted tetrahedral. The quinoxaline ring system is almost planar with a dihedral angle of 84.4 (2)degrees between the phenyl ring of the sulfonamide group and the quinoxaline ring. There is an intermolecular N-H O bond of 2.966 (6) Angstrom.