SUBCELLULAR-DISTRIBUTION AND SOME PROPERTIES OF THE CYTOCHROME-B COMPONENT OF THE MICROBICIDAL OXIDASE SYSTEM OF HUMAN-NEUTROPHILS

被引：126

作者：

SEGAL, AW ^{[1
]}

JONES, OTG ^{[1
]}

机构：

[1] UNIV BRISTOL,DEPT BIOCHEM,BRISTOL BS8 1TD,AVON,ENGLAND

来源：

BIOCHEMICAL JOURNAL | 1979年 / 182卷 / 01期

关键词：

D O I：

10.1042/bj1820181

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A novel cytochrome b has recently been described in human neutrophils. The subcellular distribution of this cytochrome was investigated by analytical fractionation on continuous sucrose gradients and it was found to have a dual localization, the major component having a similar distribution to the plasma-membrane marker [3H]concanavalin A, and a denser peak located with the specific granules. The two components were separated on discontinuous gradients and studied independently.

引用

页码：181 / 188

页数：8

共 48 条

[1] The extra respiration of phagocytosis [J].

Baldridge, CW ;

Gerard, RW .

AMERICAN JOURNAL OF PHYSIOLOGY, 1933, 103 (01) :235-236

[2] DEVICES FOR GRADIENT ELUTION IN CHROMATOGRAPHY [J].

BOCK, RM ;

LING, NS .

ANALYTICAL CHEMISTRY, 1954, 26 (10) :1543-1546

[3] ENZYMIC CHARACTERIZATION AND LIPID COMPOSITION OF RAT LIVER SUBCELLULAR MEMBRANES [J].

COLBEAU, A ;

NACHBAUR, J ;

VIGNAIS, PM .

BIOCHIMICA ET BIOPHYSICA ACTA, 1971, 249 (02) :462-+

[4]

COOPERSTEIN SJ, 1951, J BIOL CHEM, V189, P665

[5] DEFECTIVE SUPEROXIDE PRODUCTION BY GRANULOCYTES FROM PATIENTS WITH CHRONIC GRANULOMATOUS DISEASE [J].

CURNUTTE, JT ;

WHITTEN, DM ;

BABIOR, BM .

NEW ENGLAND JOURNAL OF MEDICINE, 1974, 290 (11) :593-597

[6] REDUCED NICOTINAMIDE ADENINE-DINUCLEOTIDE AND REDUCED NICOTINAMIDE ADENINE-DINUCLEOTIDE PHOSPHATE DIAPHORASE ACTIVITY IN HUMAN POLYMORPHONUCLEAR LEUKOCYTES [J].

DECHATELET, LR ;

MCPHAIL, LC ;

MULLIKIN, D ;

MCCALL, CE .

INFECTION AND IMMUNITY, 1974, 10 (03) :528-534

[7]

DEWALD B, 1975, J EXP MED, V141, P709

[8]

Dutton P L, 1978, Methods Enzymol, V54, P411

[9]

GINSBURG I, 1976, Critical Reviews in Microbiology, V4, P249, DOI 10.3109/10408417609106944

[10] PRODUCTION OF HYDROXYL AND SUPEROXIDE RADICALS BY STIMULATED HUMAN-NEUTROPHILS - MEASUREMENTS BY EPR SPECTROSCOPY [J].

GREEN, MR ;

HILL, HAO ;

OKOLOWZUBKOWSKA, MJ ;

SEGAL, AW .

FEBS LETTERS, 1979, 100 (01) :23-26

← 1 2 3 4 5 →