RESPONSE TO 3RD-LINE ENDOCRINE TREATMENT FOR ADVANCED BREAST-CANCER

被引：14

作者：

IVESON, TJ ^{[1
]}

AHERN, J ^{[1
]}

SMITH, IE ^{[1
]}

机构：

[1] ROYAL MARSDEN HOSP,BREAST UNIT,FULHAM RD,LONDON SW3 6JJ,ENGLAND

来源：

EUROPEAN JOURNAL OF CANCER | 1993年 / 29A卷 / 04期

关键词：

D O I：

10.1016/S0959-8049(05)80154-6

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In a retrospective analysis we have identified 55 patients who have received three endocrine treatments for advanced breast cancer. 42% of these patients have benefitted from third-line endocrine treatment in terms of disease stabilisation, symptom relief or objective response and this was translated into statistically significant (P<0.01) improved median survival of these patients (34 months) compared with those with progressive disease on third-line treatment (14 months). This suggests that third-line endocrine treatment might be of benefit to a number of patients with advanced breast cancer.

引用

页码：572 / 574

页数：3

共 25 条

[1] LOW-DOSE AMINOGLUTETHIMIDE WITHOUT HYDROCORTISONE FOR THE TREATMENT OF ADVANCED POSTMENOPAUSAL BREAST-CANCER [J].

BRUNING, PF ;

BONFRER, JMG ;

HART, AAM ;

VANDERLINDEN, E ;

DEJONGBAKKER, M ;

MOOLENAAR, AJ ;

NOOIJEN, WJ .

EUROPEAN JOURNAL OF CANCER & CLINICAL ONCOLOGY, 1989, 25 (02) :369-376

[2] RANDOMIZED TRIAL COMPARING AMINOGLUTETHIMIDE WITH HIGH-DOSE MEDROXYPROGESTERONE ACETATE IN THERAPY FOR ADVANCED BREAST-CARCINOMA [J].

CANNEY, PA ;

PRIESTMAN, TJ ;

GRIFFITHS, T ;

LATIEF, TN ;

MOULD, JJ ;

SPOONER, D .

JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1988, 80 (14) :1147-1151

[3]

CONTE CC, 1989, CANCER, V64, P150, DOI 10.1002/1097-0142(19890701)64:1<150::AID-CNCR2820640125>3.0.CO

[4]

2-N

[5] NORETHISTERONE ACETATE AS SECONDARY ENDOCRINE TREATMENT IN ADVANCED BREAST-CANCER [J].

DALUZ, RJM ;

RUBENS, RD .

EUROPEAN JOURNAL OF CANCER & CLINICAL ONCOLOGY, 1989, 25 (12) :1879-1880

[6]

HARRIS AL, 1982, CANCER RES, V42, P3405

[7] ASSESSMENT OF RESPONSE TO THERAPY IN ADVANCED BREAST-CANCER - PROJECT OF PROGRAM ON CLINICAL ONCOLOGY OF "INTERNATIONAL-UNION-AGAINST-CANCER, GENEVA, SWITZERLAND [J].

HAYWARD, JL ;

CARBONE, PP ;

HEUSON, JC ;

KUMAOKA, S ;

SEGALOFF, A ;

RUBENS, RD .

EUROPEAN JOURNAL OF CANCER, 1977, 13 (01) :89-94

[8] THE DEFINITION OF THE NO CHANGE CATEGORY IN PATIENTS TREATED WITH ENDOCRINE THERAPY AND CHEMOTHERAPY FOR ADVANCED-CARCINOMA OF THE BREAST [J].

HOWELL, A ;

MACKINTOSH, J ;

JONES, M ;

REDFORD, J ;

WAGSTAFF, J ;

SELLWOOD, RA .

EUROPEAN JOURNAL OF CANCER & CLINICAL ONCOLOGY, 1988, 24 (10) :1567-1572

[9]

INGLE JN, 1984, CANCER-AM CANCER SOC, V53, P766, DOI 10.1002/1097-0142(19840201)53:3+<766::AID-CNCR2820531327>3.0.CO

[10]

2-H

← 1 2 3 →