BIRTHMARKS WITH SERIOUS MEDICAL SIGNIFICANCE - NEVOCELLULAR-NEVI, SEBACEOUS-NEVI, AND MULTIPLE CAFE-AU-LAIT SPOTS

被引：111

作者：

ALPER, J

HOLMES, LB

MIHM, MC

机构：

[1] MASSACHUSETTS GEN HOSP, CHILDRENS SERV, GENET UNIT, BOSTON, MA 02114 USA

[2] MASSACHUSETTS GEN HOSP, DEPT DERMATOL, BOSTON, MA 02114 USA

[3] HARVARD UNIV, SCH MED, CTR HUMAN GENET, BOSTON, MA 02115 USA

[4] HARVARD UNIV, SCH MED, DEPT PEDIAT, BOSTON, MA 02115 USA

[5] HARVARD UNIV, SCH MED, DEPT DERMATOL, BOSTON, MA 02115 USA

来源：

JOURNAL OF PEDIATRICS | 1979年 / 95卷 / 05期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0022-3476(79)80713-1

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Birthmarks of potential medical significance were identified among 4,641 newborn infants: 1.1% had a nevocellular nevus and 0.3% had a sebaceous nevus; 1.8% of black infants, but no white infants, had three or more cafe au lait spots. The large nevocellular nevus is considered premalignant, but the significance of the small nevocellular nevus has not been established. The sebaceous nevus fades after birth but undergoes hyperplasia at puberty. Multiple cafe au lait spots-occur less commonly in white than in black infants, and are therefore of greater concern as possibly an early sign of neurofibromatosis. © 1979 The C. V. Mosby Company.

引用

页码：696 / 700

页数：5

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