TOTAL SYNTHESIS OF THE ESTERASE INHIBITOR (+/-)-EBELACTONE-A USING AN ALDOL-CLAISEN STRATEGY

被引：30

作者：

PATERSON, I

HULME, AN

机构：

[1] University Chemical Laboratory, Cambridge, CB2 1EW, Lensfield Road

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 51期

关键词：

D O I：

10.1016/S0040-4039(00)88532-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The beta-lactone (+/-)-ebelactone A has been prepared in 12 steps from diethylketone (9% overall yield) using a series of three boron enolate aldol reactions coupled with the Ireland ester enolate Claisen rearrangement, 10 --> 11.

引用

页码：7513 / 7516

页数：4

共 18 条

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