NADPH-O2 OXIDOREDUCTASE OF HUMAN EOSINOPHILS IN THE CELL-FREE SYSTEM

被引：23

作者：

BOLSCHER, BGJM

KOENDERMAN, L

TOOL, ATJ

STOKMAN, PM

ROOS, D

机构：

[1] NETHERLANDS RED CROSS,BLOOD TRANSFUS SERV,CENT LAB,POB 9406,1006 AK AMSTERDAM,NETHERLANDS

[2] UNIV AMSTERDAM,EXPTL & CLIN IMMUNOL LAB,AMSTERDAM,NETHERLANDS

来源：

FEBS LETTERS | 1990年 / 268卷 / 01期

关键词：

Cell-free system; Eosinophil; NADPH oxidase;

D O I：

10.1016/0014-5793(90)81025-J

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The NADPH oxidase of human eosinophils, measured in the cell-free system, shows the same characteristics as the enzyme from human neutrophils. All proteins required for activity of the enzyme are expressed in eosinophils at a higher level than in neutrophils. Eosinophils isolated from patients with chronic granulomatous disease show the same molecular defects as the neutrophils fom these patients. © 1990.

引用

页码：269 / 273

页数：5

共 21 条

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