SYNTHESIS AND BIOLOGICAL-ACTIVITY OF CARBOCYCLIC DERIVATIVES OF THE POTENT ANTIVIRAL AGENT 9-[2-(PHOSPHONOMETHOXY)ETHYL]GUANINE (PMEG)

被引：15

作者：

BRONSON, JJ

FERRARA, LM

MARTIN, JC

MANSURI, MM

机构：

[1] Bristol-Myers Squibb Company, Pharmaceutical Research Institute, Wallingford, CT 06492-7660

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1992年 / 2卷 / 07期

关键词：

D O I：

10.1016/S0960-894X(00)80391-1

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Carbocyclic analogues of the potent nucleotide analogue 9-[2-(phosphonomethoxy)ethyl]guanine (PMEG) were prepared and evaluated for antiviral activity against herpes simplex virus type 2 and human immunodeficiency virus.

引用

页码：685 / 690

页数：6

共 15 条

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