SYNTHESIS AND BIOLOGICAL-ACTIVITY OF CARBOCYCLIC DERIVATIVES OF THE POTENT ANTIVIRAL AGENT 9-[2-(PHOSPHONOMETHOXY)ETHYL]GUANINE (PMEG)

被引:15
作者
BRONSON, JJ
FERRARA, LM
MARTIN, JC
MANSURI, MM
机构
[1] Bristol-Myers Squibb Company, Pharmaceutical Research Institute, Wallingford, CT 06492-7660
关键词
D O I
10.1016/S0960-894X(00)80391-1
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Carbocyclic analogues of the potent nucleotide analogue 9-[2-(phosphonomethoxy)ethyl]guanine (PMEG) were prepared and evaluated for antiviral activity against herpes simplex virus type 2 and human immunodeficiency virus.
引用
收藏
页码:685 / 690
页数:6
相关论文
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