Proteolytic cleavage of the repressor (BlaI) of beta-lactamase synthesis in Staphylococcus aureus

被引：22

作者：

Lewis, RA ^{[1
]}

Curnock, SP ^{[1
]}

Dyke, KGH ^{[1
]}

机构：

[1] Univ Oxford, Dept Biochem, Microbiol Unit, Oxford OX1 3QU, England

来源：

FEMS MICROBIOLOGY LETTERS | 1999年 / 178卷 / 02期

基金：

英国生物技术与生命科学研究理事会;

关键词：

BlaI; BlaR1; beta-lactamase; Staphylococcus aureus;

D O I：

10.1016/S0378-1097(99)00366-3

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The proteolytic cleavage of BlaI was shown to correlate with beta-lactamase synthesis in Staphylococcus aureus. BlaI was found to be autoregulatory when expressed from the blaZ promoter. Insertion of a 10-bp linker into the SnaBI site of blaRI resulted in constitutive synthesis of beta-lactamase. (C) 1999 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.

引用

页码：271 / 275

页数：5

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