SEPARATION OF RELAXIN ACTIVITIES IN EXTRACTS OF OVARIES OF PREGNANT SOWS BY POLYACRYLAMIDE-GEL ELECTROPHORESIS

被引：8

作者：

OLIVER, RM ^{[1
]}

FIELDS, PA ^{[1
]}

LARKIN, LH ^{[1
]}

机构：

[1] UNIV FLORIDA,COLL MED,JHMHC,GAINESVILLE,FL 32610

来源：

JOURNAL OF ENDOCRINOLOGY | 1978年 / 76卷 / 03期

关键词：

D O I：

10.1677/joe.0.0760517

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Polyacrylamide gel electrophoresis has been employed to separate three fractions that have relaxin activity from crude extracts of ovaries of pregnant sows. Bioassays indicated that all fractions had the ability to inhibit spontaneous uterine contractions in vitro and to induce formation of interpubic ligaments in oestrogen-primed mice. The presence of the various fractions in crude extracts of sow ovaries was monitored with the polyacrylamide gel system on days 40, 70 and 100 of pregnancy. Both the total amount and the relative proportions of the fractions were found to change as pregnancy progressed.

引用

页码：517 / 525

页数：9

共 17 条

[1] RELAXIN IN PORCINE CORPORA-LUTEA DURING PREGNANCY AND AFTER HYSTERECTOMY [J].