SMOKING DOES AFFECT FECUNDITY

被引:42
作者
SUONIO, S
SAARIKOSKI, S
KAUHANEN, O
METSAPELTO, A
TERHO, J
VOHLONEN, I
机构
[1] HLTH CTR TAMPERE,TAMPERE,FINLAND
[2] UNIV KUOPIO,DEPT OBSTET & GYNAECOL,SF-70211 KUOPIO 21,FINLAND
[3] UNIV HELSINKI,SF-00100 HELSINKI 10,FINLAND
来源
EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 1990年 / 34卷 / 1-2期
关键词
Conception delay; Fecundity; Smoking;
D O I
10.1016/0028-2243(90)90011-O
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
A total of 2198 mothers were interviewed at the 20th week of pregnancy and their smoking habits before pregnancy and the time from discontinuation of contraception to the beginning of the pregnancy were registered. This information was used to investigate whether smoking affects conception delay; i.e., fecundity and a multifactorial analysis were used. The longer the conception delay, the more significant was the deleterious effect of even light smoking, the odds ratio shifting from 1.1 at 6 months to 3.2 at 18 months. The effect of smoking on fecundity seemed to be mostly dose-dependent. In mothers becoming successfully pregnant in 12 months, both maternal and paternal smoking increased the risk of conception delay (OR 1.5 and 1.3), and the effect was potentiated by increasing age (OR 2.3 and 1.6). In addition to smoking, previous recurrent spontaneous abortions were also associated with fecundity. © 1990.
引用
收藏
页码:89 / 95
页数:7
相关论文
共 14 条
  • [1] CIGARETTE-SMOKING ASSOCIATED WITH DELAYED CONCEPTION
    BAIRD, DD
    WILCOX, AJ
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1985, 253 (20): : 2979 - 2983
  • [2] DIXON WJ, 1983, BMDP STATISTICAL SOF
  • [3] HARLAP S, 1984, INT J FERTIL, V29, P73
  • [4] HARLAP S, 1987, SMOKING REPRODUCTIVE, P75
  • [5] EFFECTS OF AGE, CIGARETTE-SMOKING, AND OTHER FACTORS ON FERTILITY - FINDINGS IN A LARGE PROSPECTIVE-STUDY
    HOWE, G
    WESTHOFF, C
    VESSEY, M
    YEATES, D
    [J]. BRITISH MEDICAL JOURNAL, 1985, 290 (6483) : 1697 - 1700
  • [6] LINN S, 1982, JAMA-J AM MED ASSOC, P247
  • [7] MALMCOLM S, 1978, AM J DRUG ALCOHOL AB, V5, P87
  • [8] THE EFFECTS OF SMOKING ON FERTILITY FROM GAMETOGENESIS TO IMPLANTATION
    MATTISON, DR
    [J]. ENVIRONMENTAL RESEARCH, 1982, 28 (02) : 410 - 433
  • [9] OLSEN J, 1982, INT J EPIDEMIOL, V12, P179
  • [10] PHIPPS WR, 1987, FERTIL STERIL, V3, P380