RANDOMIZED TRIAL OF DOXYCYCLINE VERSUS JOSAMYCIN FOR MEDITERRANEAN SPOTTED-FEVER

被引：35

作者：

BELLA, F

FONT, B

URIZ, S

MUNOZ, T

ESPEJO, E

TRAVERIA, J

SERRANO, JA

SEGURA, F

机构：

[1] HOSP TERRASSA,DEPT PEDIAT,E-08227 TERRASSA,SPAIN

[2] HOSP SABADELL,DEPT INTERNAL MED,E-08208 SAVADELL,SPAIN

[3] HOSP SABADELL,DEPT PEDIAT,E-08208 SABADELL,SPAIN

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1990年 / 34卷 / 05期

关键词：

D O I：

10.1128/AAC.34.5.937

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We undertook a randomized clinical trial comparing therapeutic efficacy of the 1-day doxycycline regimen with the 5-day josamycin regimen for Mediteranean spotted fever. All 59 patients recovered uneventfully, and results did not significantly differ between the two schedules. One-day doxycycline therapy is an effective, easy, and inexpensive treatment. Josamycin is a useful therapeutic alternative that may be particularly convenient for pregnant women and patients with a history of allergy to tetracyclines.

引用

页码：937 / 938

页数：2

共 8 条

[1]

BELLACUETO F, 1987, J INFECT DIS, V155, P1056, DOI 10.1093/infdis/155.5.1056

[2]

FONTCREUS B, 1985, REV INFECT DIS, V7, P635

[3]

GROSSMAN ER, 1971, PEDIATRICS, V47, P567

[4] RANDOMIZED DOUBLE-BLIND EVALUATION OF CIPROFLOXACIN AND DOXYCYCLINE FOR MEDITERRANEAN SPOTTED-FEVER [J].