TOTAL SYNTHESIS OF (+/-)-PROSTAGLANDIN-E2 METHYL-ESTER FROM EXO-2-BROMOENDO-3-HYDROXYBICYCLO[3.2.0]HEPTAN-6-ONE USING DIMETHYL-TERT-BUTYLSILYL PROTECTED INTERMEDIATES

被引：26

作者：

HOWARD, C

NEWTON, RF

REYNOLDS, DP

ROBERTS, SM

机构：

[1] GLAXO GRP RES LTD,DEPT CHEM RES,WARE SG12 0DJ,HERTFORDSHIRE,ENGLAND

[2] UNIV SALFORD,RAMAGE LABS,DEPT CHEM & APPL CHEM,SALFORD M5 4WT,LANCASHIRE,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1981年 / 07期

关键词：

D O I：

10.1039/p19810002049

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：2049 / 2054

页数：6

共 11 条

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[7] TOTAL SYNTHESIS OF PROSTAGLANDIN-E2 BY REARRANGEMENT OF A 6,8-DISUBSTITUTED-2-OXABICYCLO[3.2.1]OCTAN-3-ONE TO A 4,5-DISUBSTITUTED-PERHYDROCYCLOPENTA[B]FURAN-2-ONE
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[8] A SHORT AND EFFICIENT TOTAL SYNTHESIS OF (+/-) PROSTAGLANDIN-D2 METHYL-ESTER INVOLVING A NEW METHOD FOR THE CLEAVAGE OF A DIMETHYL-TERT-BUTYLSILYL ETHER
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ROBERTS, SM
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1981, (07): : 2055 - 2058
[9] NOVEL SYNTHESIS OF PROSTAGLANDIN-E2 INVOLVING REGIOSELECTIVE RING-OPENING OF A 2,3-ENDO-EPOXYBICYCLO[3.2.0]HEPTAN-6-ONE ACETAL WITH A MIXED ORGANOCUPRATE REAGENT
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[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1978, (15) : 662 - 664
[10] TORISAWA Y, 1979, TETRAHEDRON LETT, P1865

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