SIMPLE SEQUENCE REPEAT LENGTH POLYMORPHISMS MAPPED TO RAT CHROMOSOME-11

被引：5

作者：

DU, Y

REMMERS, EF

GOLDMUNTZ, EA

ZHA, H

MATHERN, P

CROFFORD, LJ

WILDER, RL

机构：

来源：

CYTOGENETICS AND CELL GENETICS | 1994年 / 65卷 / 03期

关键词：

D O I：

10.1159/000133629

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Two genes and two anonymous DNA loci were mapped to rat chromosome 11 using F2 intercross progeny of Fischer (F344/N) and Lewis (LEW/N) inbred rats. These four loci formed a single linkage group covering 21.5 cM with the following map order: somatostatin (SST)-D11N161-D11N18-cell surface protein (MOX2). These four loci were typed by PCR-based simple sequence repeat (SSR) length polymorphism detection. For each marker four to seven different alleles were detected using a panel of 13 inbred rat strains (F344/N, LEW/N, BN/SsN, BUF/N, LER/N, MR/N, MNR/N, LOU/MN, ACI/N, WBB1/N, WBB2/N, SHR/N, WKY/N). Comparative gene mapping analysis suggests syntenic conservation between rat chromosome 11 and mouse Chromosome 16.

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页码：186 / 189

页数：4

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