HIGH-FREQUENCY OF CYTOTOXIC PRECURSOR CELLS FOR A SYNGENEIC TUMOR

被引：15

作者：

WARREN, HS ^{[1
]}

LAFFERTY, KJ ^{[1
]}

机构：

[1] AUSTRALIAN NATL UNIV,JOHN CURTIN SCH MED RES,DEPT IMMUNOL,CANBERRA 2601,ACT,AUSTRALIA

来源：

SCANDINAVIAN JOURNAL OF IMMUNOLOGY | 1979年 / 10卷 / 04期

关键词：

D O I：

10.1111/j.1365-3083.1979.tb01362.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The average frequency of cytotoxic precursor cells in DBA/2 lymph node cell preparations reactive to the syngeneic tumour P815 has been determined as 1 in 2000. This frequency is similar to the precursor frequency for an allogeneic tumour EL‐4. The normal lack of response of DBA/2 lymph node cells to the syngeneic tumour P815 in vitro cannot be attributed to a lack of cytotoxic precursor cells. We conclude that in this tumour‐host system non‐immunogenicity reflects a defect at the inductive step. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：349 / 352

页数：4

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