CERIUM CHLORIDE-CATALYZED ADDITION OF GRIGNARD-REAGENTS TO VINYLOGOUS ESTERS - AN IMPROVED ROUTE TO 3-SUBSTITUTED CYCLOPENT-2-EN-1-ONES

被引：10

作者：

CRIMMINS, MT

DEDOPOULOU, D

机构：

[1] Venable and Kenan Laboratories of Chemistry, University of North Carolina at Chapel Hill

来源：

SYNTHETIC COMMUNICATIONS | 1992年 / 22卷 / 13期

基金：

美国国家卫生研究院; 美国国家科学基金会;

关键词：

D O I：

10.1080/00397919208021326

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Addition of Grignard reagents to vinylogous esters in the presence of cerium chloride results in an improved one-pot synthesis of 3-substituted cyclopent-2-en-1-ones.

引用

页码：1953 / 1958

页数：6

共 16 条

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[5]

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[7]

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[8] FREE-RADICAL CARBON-CARBON BOND FORMATION IN ORGANIC-SYNTHESIS [J].

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[9] ORGANOCERIUM REAGENTS - NUCLEOPHILIC-ADDITION TO EASILY ENOLIZABLE KETONES [J].

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[10] REACTIONS OF CARBONYL-COMPOUNDS WITH GRIGNARD-REAGENTS IN THE PRESENCE OF CERIUM CHLORIDE [J].

IMAMOTO, T ;

TAKIYAMA, N ;

NAKAMURA, K ;

HATAJIMA, T ;

KAMIYA, Y .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1989, 111 (12) :4392-4398

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