THE 1ST ASYMMETRIC-SYNTHESIS OF POLYFUNCTIONALIZED 4H-PYRANS VIA MICHAEL ADDITION OF MALONONITRILE TO 2-ACYL ACRYLATES

被引：8

作者：

GONZALEZ, R

MARTIN, N

SEOANE, C

MARCO, JL

ALBERT, A

CANO, FH

机构：

[1] UNIV COMPLUTENSE MADRID,FAC QUIM,DEPT QUIM ORGAN,E-28040 MADRID,SPAIN

[2] CSIC,INST QUIM ORGAN,E-28006 MADRID,SPAIN

[3] CSIC,INST ROCASOLANO,UEI CRISTALOG,E-28006 MADRID,SPAIN

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 26期

关键词：

D O I：

10.1016/0040-4039(92)80031-E

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Starting from (R)-2,3-O-isopropylideneglyceraldehyde, the first asymmetric synthesis of 4H-pyrans (4BAR) has been developed; a de tailed X-ray structural and stereochemical study has established as R the absolute configuration at the new stereocenter in compounds 4.

引用

页码：3809 / 3812

页数：4

共 13 条

[1]

ALONSOCE.F, 1972, AN QUIM-INT, V68, P285

[2]

APARICIO FJL, 1982, CARBOHYD RES, V103, P158

[3]

APARICIO FJL, 1983, CARBOHYD RES, V115, P250

[4] RING TRANSFORMATION OF ISOXAZOLES INTO FURAN AND PYRAN DERIVATIVES [J].