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THE MOLECULAR-BIOLOGY OF CYSTIC-FIBROSIS

被引：38
作者：
SFERRA, TJ
COLLINS, FS
机构：
[1] UNIV MICHIGAN, DEPT COMMUNICABLE DIS, ANN ARBOR, MI 48109 USA
[2] UNIV MICHIGAN, DEPT PEDIAT, ANN ARBOR, MI 48109 USA
[3] UNIV MICHIGAN, DEPT INTERNAL MED, ANN ARBOR, MI 48109 USA
[4] UNIV MICHIGAN, HOWARD HUGHES MED INST, ANN ARBOR, MI 48109 USA
来源：
ANNUAL REVIEW OF MEDICINE | 1993年 / 44卷
关键词：
CFTR; GENETICS; ION CHANNELS;
D O I：
10.1146/annurev.med.44.1.133
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Cystic fibrosis afflicts many children and, as the life expectancy for patients with this disease steadily increases, many adults as well. The identification and characterization of the gene responsible for this disorder provide a basis for understanding the pathophysiology of cystic fibrosis. Basic science advances are rapidly being integrated into the diagnostic and therapeutic regimens used by physicians in the care of patients with this disease.
引用
收藏
页码：133 / 144
页数：12
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